General
Brazil have made one world championship appearance in the mixed 4x100m medley relay, setting the ninth-fastest time in the heats in 2015 in Kazan.
The Brazilians won the inaugural mixed 4x100m medley relay at the Pan American Games in 2019 in Lima. Although they touched home in second place, they were promoted to the gold medal position because the United States of America were disqualified after their breaststroke swimmer was adjudged to have made two dolphin kicks off the turn.
Brazil were bronze medallists at the 2021 South American Championships in Buenos Aires, finishing behind Colombia and Argentina.